Artificial Kidney Prize, Phase 2

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Think better, think bold, think big

Seeking artificial kidney innovations from the cellular, tissue, and organ bioengineering communities.



This Competition solicits applications that support innovations in regenerative medicine, cellular engineering, tissue engineering, systems biology, and synthetic biology to either advance the development of a bioartificial kidney prototype or create enabling tools that address key challenges for developing an artificial kidney platform. With the Artificial Kidney Prize, HHS and ASN intend to stimulate the market for further kidney health innovation, drawing greater participation and capital.

Overview

People with kidney diseases need kidney replacement therapies that increase survival and improve quality of life. Innovation is urgently needed – but also incredibly difficult: a functioning kidney is built from over 26 different cell types that seamlessly integrate to maintain homeostasis. KidneyX aims to increase the options for treating people with kidney diseases—including the creation of a bioartificial kidney. The first phase of the Artificial Kidney Prize (awarded in Fall 2021) sought solutions to enable and advance the functionality, effectiveness, and/or reliability of artificial kidneys. This phase of the Artificial Kidney Prize aims to accelerate the development of an artificial kidney from the regenerative medicine, cellular engineering, tissue engineering, systems biology, and synthetic biology communities.

Learn More about KidneyX and the Artificial Kidney Prize Phase 2


Innovative Solutions, Two Tracks


Track One: Accelerating the Prototype Bioartificial Kidney

Track One solicits applications that apply innovations in regenerative medicine, cellular engineering, systems biology, and synthetic biology to advance the development of a bioartificial kidney prototype. Track One offers a space for scientists, professionals in the medical field, people with kidney diseases, companies, and innovators to expand on their institutional knowledge and work toward innovative changes.

  • Entrants to Track One must have a clear path to a prototype bioartificial kidney informed by patient input, as well as a milestone-based timeline to first-in-human studies.
  • Submissions close October 28, 2022

Learn more about Track 1


Track Two: Components and Tools that Enable the Development of an Artificial Kidney

Track Two solicits applications that apply innovations in regenerative medicine and similar cell-based methods to develop tools or components that enable advances in artificial kidneys. Such enabling tools could optimize efficiency and scalability or address other critical technical challenges faced by artificial kidney developers. We particularly welcome submissions from scientists, companies, and innovators who work outside the kidney space and/or are still laying the foundational framework for their projects.

  • Entrants to Track Two must clearly describe how their tool adapts innovations and methods from fields such as regenerative medicine, cellular engineering, systems biology, and/or synthetic biology to solve a particular challenge for developing artificial kidneys. For this competition, artificial kidneys may be wearable or implantable options for kidney replacement therapy and developed as a bioengineered, xenotransplant, chimera, or another non-human organ platform.
  • Previous experience with bioartificial kidneys is not necessary for Track Two applicants.
  • Submissions close January 28, 2023

Learn more about Track 2

Awards: $10.5 Million in Prizes

For Phase 2, $10.5 million in funding is available, with prizes divided across both tracks. At the discretion of HHS and ASN, it is anticipated that up to three (3) Track One winners will divide $4.5 million in funding, while up to six (6) Track Two winners will divide $6 million in funding.

Submission and Eligibility Requirements

All entrants must review the Announcement of Requirements and Registration for full award details; eligibility requirements; registration and submission requirements; evaluation criteria; judging information; and other competition rules, terms, and conditions prior to submission.

Questions? Email kidneyx@asn-online.org. Answers will be provided on our FAQ page.

Entrant Support and Resources

A range of resources are available for entrants to learn more about kidney health and function, the KidneyX program, and to be able to connect with other interested individuals for potential collaborations.