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Artificial Kidney Prize, Phase 2: Track One

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Current Competition

Track One: Accelerating the Prototype Bioartificial Kidney

Track One of the Artificial Kidney Prize advances bioartificial kidney prototypes toward first-in-human studies

 

Overview

Track One solicits applications that apply innovations and methods in regenerative medicine, cellular engineering, systems biology, and synthetic biology to advance the development of a bioartificial kidney prototype.

Entrants’ solutions to Track One should include clear descriptions of their development plans for a prototype bioartificial kidney, including a pathway and future timeline toward first-in-human studies. Submissions could be supported by pre-clinical (bench or animal) or clinical data demonstrating the potential of the approach to support the reliability, effectiveness, and functionality of wearable or implantable bioartificial kidneys.

Track One offers a space for scientists, professionals in the medical field, people with kidney diseases, and innovators to expand on their institutional knowledge to work toward innovative change.

Total prize amount:$4.5 Million

Up to 3 winners

Key Competition Dates

  • Submission period opened: August 10, 2022
  • Submission period closed: October 28, 2022 at 4:59 p.m. EST
  • Winners announced by: April 2023

Judging Criteria

Functionality Replication

The degree to which patient input has framed the targeted functions and design of the prototype. The degree of confidence that the plans for bioartificial kidney prototype will achieve critical kidney functions safely and continuously. See Technology Roadmap for Innovative Approaches to Renal Replacement Therapy for examples of kidney functionality.

Level of Innovation

The degree to which the submission demonstrates a novel adaptation of regenerative medicine, cellular engineering, systems biology, and/or synthetic biology in the development of a prototype bioartificial kidney.

Preliminary Proof of Concept

The likelihood that future objectives are achievable in advancing a prototype of a bioartificial kidney towards animal studies, first-in-human studies, and/or clinical trials.

Development Progress and Plan

The amount of progress completed relative to funding received, the rigor of plans, and the confidence in the team to execute. The degree of patient engagement in the design and/or evaluation of a prototype. Plans that describe the work needed beyond the submission should include future critical milestones, timelines, and collaborations to achieve animal studies, first-in-human studies, and clinical trials.

Rules, Terms, & Eligibility

Review the Announcement of Requirements and Registration for:

  • Full award details
  • Eligibility requirements
  • Registration and submission requirements
  • Evaluation criteria
  • Judging information
  • Other competition rules, terms, and conditions