Artificial Kidney Prize, Phase 2: Track 2

Components and Tools that Enable the Development of an Artificial Kidney

Think better, think bold, think big


Track Two of the Artificial Kidney Prize supports the creation of enabling tools for artificial kidney platform development.

Overview

Track Two solicits applications to develop enabling tools that apply innovations and methods from regenerative medicine, cellular engineering, systems biology, and/or synthetic biology to address a challenge faced in the development of artificial kidneys. For this competition, artificial kidneys may be wearable or implantable options for kidney replacement therapy and developed as a bioengineered, xenotransplant, chimera, or another non-human organ platform. Entrants' solutions to Track Two should include clear descriptions of the challenge and barrier faced by artificial kidney developers, with supporting rationale and data to support how the proposed tool or component from regenerative medicine, cellular engineering, systems biology, and/or synthetic biology will enable the development of an artificial kidney platform.

We particularly welcome submissions from scientists, companies, and other innovators who work outside the kidney space and have innovations that will overcome barriers for developing an artificial kidney and/or are still laying the foundational framework for their projects.

Award Details

At the discretion of HHS and ASN, it is anticipated that up to six (6) Track Two winners will divide $6 million in funding.

Timeline

Submission period begins: August 10, 2022

Submission period ends: January 28, 2023, at 4:59 p.m. ET

Winners announced by: June 2023

Judging Criteria

Functionality Replication: The degree of justification and confidence that the enabling tool or component(s) address a critical challenge in the development of an artificial kidney platform. See Technology Roadmap for Innovative Approaches to Renal Replacement Therapy for examples of kidney functionality.

Level of Innovation: The degree to which the submission identifies a barrier in the development of an artificial kidney platform and describes how an enabling tool can be created through an adaptation of regenerative medicine, cellular engineering, systems biology, and/or synthetic biology, beyond established scientific methods and technology.

Preliminary Proof of Concept: The likelihood of success that the application of regenerative medicine, cellular engineering, systems biology, and/or synthetic biology concepts towards the development of an enabling tool or component can be created to address a challenge in developing an artificial kidney platform.

Development Progress and Plan: The amount of progress completed relative to funding received, the rigor of plans, and the confidence in the team to execute. Plans that describe the work needed beyond the submission include future critical milestones and collaborations.

Rules, Terms, and Conditions

All entrants must review the Announcement of Requirements and Registration for full award details; eligibility requirements; registration and submission requirements; evaluation criteria; judging information; and other competition rules, terms, and conditions prior to submission.

Questions? Email KidneyX@asn-online.org. Answers will be provided on our FAQ page.

Entrant Support and Resources

KidneyX provides a range of resources for entrants to inform their applications and facilitate collaboration

Submit Application